格伦德费斯特在很长一段时间里都保持着电火花派身份,甚至在埃克尔斯和其他大多数神经生理学家都已经确信了突触传递的化学本质之后。直到1954年9月,我进入他实验室之前一年,格伦德费斯特才在一本重要的关于神经冲动的专题论文集中转变了看法。他写道:“埃克尔斯最近已经接受了这种(神经细胞到神经细胞的)传递是化学介导的观点。我们中有些人反对这一观点。……我们可能是错误的。”(D. Nachmansohn and H. H. Merrit, eds., Nerve Impulses; Transactions[New York: Josiah Macy Jr. Foundation, 1956], 第184页。)
对于突触传递的研究历程,参见W. M. Cowan and E. R. Kandel, “A brief history of synapses and synaptic transmission,” in Synapses, ed. W. M. Cowan, T. C. Südhof, and C. F. Stevens, 1–87 (Baltimore: Johns Hopkins University Press, 2000).
伯纳德·卡茨讲述他到达英国的见闻出自“To tell you the truth, sir, we do it because it’s amusing!” in The History of Neuroscience in Autobiography, ed. L. R. Squire, vol. 1, 348–81 (Washington, D.C.: Society for Neuroscience, 1996); 引文摘自第373页。
有关埃克尔斯对波普尔的描述,参见他的“Under the spell of the synapse,” in The Neurosciences: Paths of Discovery, ed. F. G. Worden, J. P. Swazey, and G. Adelman, 159–80 (Cambridge, Mass.: MIT Press, 1976); 引文摘自第162–63页。对于其他有关突触研究历程和汤与电火花之争的回忆录,参见S. R. Cajal, Recollections of My Life, trans. E. H. Craigie and J. Cano,Am. Philos. Soc. Mem. 8 (1937); H. H. Dale, “The beginnings and the prospects of neurohumoral transmission,” Pharmacol. Rev. 6 (1954): 7–13; O. Loewi, From the Workshop of Discoveries(Lawrence: University of Kansas Press, 1953). 保罗·法特对突触传递的综述是“Biophysics of junctional transmission,” Physiol. Rev. 34 (1954): 674–710; 引文摘自第704页。
本章其他信息参考了以下文献:
Brown, G. L., H. H. Dale, and W. Feldberg. “Reactions of the normal mammalian muscle to acetylcholine and eserine.” J. Physiol. 87 (1936): 394–424.
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Grundfest, H. “Synaptic and ephaptic transmission.” In Handbook of Physiology. Section I: Neurophysiology, 147–97. Washington, D.C.: American Physiological Society, 1959.
Kandel, E. R., J. H. Schwartz, and T. M. Jessell. Principles of Neural Science. 4th ed. New York: McGraw-Hill, 2000.
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Loewi, O., and E. Navratil. “On the humoral propagation of cardiac nerve action. Communication X: The fate of the vagus substance.” In Cellular Neurophysiology: A Source Book, edited by I. Cooke and M. Lipkin Jr., 478–85. New York: Holt, Rinehart & Winston, 1972.(原始德语版出版于1926年。)
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