基因修饰小鼠方法的发展，在以下论文中有描述：R. L. Brinster and R. D. Palmiter. “Induction of foreign genes in animals.” Trends Biochem. Sci. 7 (1982): 438–40; 和M. R. Capecchi, “High-efficiency transformation by direct microinjection of DNA into cultured mammalian cells.” Cell22, no. 2 (1980): 479–88.
基因敲除对长时程增强和空间记忆的影响的首次报道参见S. G. N. Grant, T. J. O’Dell, K. A. Karl, P. L. Stein, P. Soriano, and E. R. Kandel, “Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice.” Science258 (1992): 1903–10; A. J. Silva, R. Paylor, J. M. Wehner, and S. Tonegawa, “Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice.” Science257 (1992): 206–11.
与史蒂文·西格尔鲍姆合作的实验在第9章也提到过，是由马特·诺兰和乔什·杜德曼实施的。对实验的描述参见M. F. Nolan, G. Malleret, J. T. Dudman, D. Buhl, B. Santoro, E. Gibbs, S. Vronskaya, G. Buzsáki, S. A. Siegelbaum, E. R. Kandel, and A. Morozov, “A behavioral role for dendritic integration: HCN1 channels constrain spatial memory and plasticity at inputs to distal dendrites of CA1 pyramidal neurons.” Cell119 (2004): 719–32.
本章其他信息参考了以下文献：
Mayford, M., T. Abel, and E. R. Kandel. “Transgenic approaches to cognition.” Curr. Opin. Neurobiol. 5 (1995): 141–48.
Mayford, M., M. E. Bach, Y.-Y. Huang, L. Wang, R. D. Hawkins, and E. R. Kandel. “Control of memory formation through regulated expression of a CaMLIIα transgene.” Science274 (1996): 1678–83.
Mayford, M., D. Baranes, K. Podyspanina, and E. R. Kandel. “The 3’-untranslated region of CaMLIIα is a cis-acting signal for the localization and translation of mRNA in dendrites.” Proc. Natl. Acad. Sci. USA 93 (1996): 13250–55.
Silva, A. J., C. F. Stevens, S. Tonegawa, and Y. Wang. “Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase-II mutant mice.” Science257 (1992): 201–6.
Tsien, J. Z., D. F. Chen, D. Gerber, C. Tom, E. H. Mercer, D. J. Anderson, M. Mayford, E. R. Kandel, and S. Tonegawa. “Subregion and cell-type restricted gene knockout in mouse brain.” Cell87 (1996): 1317–26.
Tsien, J. Z., P. T. Huerta, and S. Tonegawa. “The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory.” Cell87 (1996): 1327–38.
