[1]INGALLS A M, DICKIE M M, SNELL G D.Obese, a new mutation in the house mouse[J].Journal of Heredity,1950,41(12):317-318.
[2]HUMMEL K P, DICKIE M M, COLEMAN D L.Diabetes, a new mutaton in the mouse[J].Science,1966,153(3740):1127-1128.
[3]COLEMAN D L, HUMMEL K P.Effects of parabiosis of normal with genetically diabetic mice[J].American Journal of Physiology,1969,217(5):1298-1304.
[4]COLEMAN D L.Effects of parabiosis of obese with diabetes and normal mice[J].Diabetologia,1973,9(4):294-298.
[5]BAHARY N, LEIBEL R L, JOSEPH L, et al.Molecular mapping of the mouse db mutation[J].Proceedings of the National Academy of Sciences of the United States of America,1990,87(21):8642-8646.
[6]BAHARY N, ZORICH G,PACHTER JE, et al.Molecular genetic linkage maps of mouse chromosomes 4 and 6[J].Genomics,1991,11(1):33-47.
[7]FRIEDMAN J M, LEIBEL R L, SIEGEL D S, et al.Molecular mapping of the mouse ob mutation[J].Genomics,1991,11(4):1054-1062.
[8]ZHANG Y, et al.Positional cloning of the mouse obese gene and its human homologue[J].Nature,1994,372(6505):425-432.
[9]TARTAGLIA L A, et al.Identification and expression cloning of a leptin receptor, OB-R[J].Cell,1995,83(7):1263-1271.
[10]FRIEDMAN J M, HALAAS J L.Leptin and the regulation of body weight in mammals[J].Nature,1998,395(6704):763-770.
[11]COLEMAN D L.A historical perspective on leptin[J].Nature,2010,Medicine 16(10):1097-1099.[12]LOFFREDO FRANCESCO S, et al.Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy[J].Cell,2013,153(4):828-839.
[13]FRIEDMAN J.20 YEARS OF LEPTIN:Leptin at 20:an overview[J].Journal of Endocrinology,2014,223(1):T1-T8.
[14]KATSIMPARDI L, et al.Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors[J].Science,2014,344(6184):630-634.
[15]LAVIANO A.Young blood[J].New England Journal of Medicine,2014,371(6):573-575.
[16]KAISER J.‘Rejuvenating'protein doubted[J].Science,2015,348(6237):849-849.